Sol-gel based evanescent wave DNA biosensors for mycoplasma detection and medical diagnosis

 

The main target of the introduced project is to fabricate novel fiber-optic based biosensors that would revolutionize the biosensor technology of the world.  In doing so we aimed at developing a label free DNA based biosensor, with an extraordinarily high sensitivity and an outstanding reliability, primarily for the detection of mycoplasm species responsible for the contamination of cell cultures, secondarily for the viral and bacterial pathogens threatening human health, and finally for the diagnosis and evaluation of genetic diseases and susceptibility (single nucleotide polymorphism, SNPs) factors for humankind respectively.

Magnesium, Manganese and Silicon Doped Hydroxyapatite Thin Films

 

Study includes synthesis of hydroxyapatite solutions with variying concentrations of dopant via sol-gel method. Thin films are deposited on metal substrates via dip-coating method. The microstructures, surface roughness, morphology and biocompatibility of the samples are being investigated.

Bioactive Glass Coatings

 

Hydoxyapatite thin film coatings on metal substrates are fabricated via sol-gel procedure. After appropriate heat treatment of the samples, bioactive glass solutions are coated with the same method. Biological and microstructural properties of the surface are being observed.